TrumpRx and IVF: What Fertility Patients Need to Know

If you’re preparing for in vitro fertilization (IVF), you may be wondering whether TrumpRx could help lower the cost of your fertility medications. The federal prescription drug platform includes discounted pricing on several medications commonly used during IVF, including Gonal-f®, Cetrotide®, and Ovidrel®, along with a growing number of generic medications.

TrumpRx is one of several developments that have followed the administration’s broader efforts to address IVF access and affordability since President Trump signed an executive order on IVF in February 2025. But for patients considering treatment today, the most important questions are practical ones: Which fertility medications are available through TrumpRx, how much could you save, and will the program actually apply to your treatment plan?

Below, we break down which IVF and fertility medications are available through TrumpRx, how the platform works, and what to consider when comparing your medication costs.

Common Medications Used During IVF

IVF typically involves several medications at different stages of treatment. Your exact medication protocol will depend on factors such as your age, ovarian reserve, diagnosis, and how your ovaries are expected to respond to treatment.

Some of the most common types of IVF medications include:

• Ovarian stimulation medications: Injectable medications such as Gonal-f®, Follistim AQ®, and Menopur® help stimulate the ovaries so multiple eggs can develop during an IVF cycle.
• Medications that prevent premature ovulation: Drugs such as Cetrotide® and Ganirelix® help prevent the ovaries from releasing eggs before the scheduled egg retrieval.
• Trigger medications: Medications such as Ovidrel®, Pregnyl®, Novarel®, or Lupron® may be used to trigger the final maturation of the eggs before retrieval.
• Hormonal support: Progesterone and, in some treatment protocols, estrogen may be used to prepare and support the uterine lining around embryo transfer.

Because IVF protocols are individualized, you may use some, but not all, of these medications during treatment. This also means the potential impact of TrumpRx will depend largely on which fertility medications your specialist prescribes.

Which Fertility Medications Are Available on TrumpRx?

TrumpRx includes discounted pricing for several medications commonly used during IVF. However, not every fertility medication on the platform is offered through the same type of discount.

Three of the most notable fertility medications included in TrumpRx are:

• Gonal-f® — an ovarian stimulation medication used to encourage the development of multiple eggs
• Cetrotide® — a medication used to prevent ovulation before egg retrieval
• Ovidrel® — a trigger shot used to help mature eggs before retrieval

These medications are manufactured by EMD Serono, which entered into a fertility medication pricing agreement with the federal government. Through TrumpRx, eligible patients paying out of pocket can access substantially reduced prices on these medications. Patients with insurance should compare the TrumpRx price with their insurance copay to determine which option may cost less.

TrumpRx Now Includes Generic Fertility Medications, Too

In May 2026, TrumpRx expanded to include cash-price comparisons for more than 600 generic medications. These listings are separate from the negotiated discounts available for certain brand-name drugs and allow patients to compare cash prices available through participating pharmacies and pharmacy discount programs.

The expanded platform includes ganirelix acetate, a generic medication commonly used during IVF to help prevent premature ovulation, as well as generic progesterone formulations, which may be prescribed for hormonal support during fertility treatment.

As TrumpRx continues to add medications and pricing options, patients may find additional fertility drugs through the platform beyond the original Gonal-F, Cetrotide, and Ovidrel discounts.

Not Every IVF Medication Is Included

Even with the expanded selection, TrumpRx does not necessarily include every medication that may be prescribed during fertility treatment. IVF protocols can involve several medications, and the specific drugs, dosages, and formulations prescribed vary from patient to patient.

This means TrumpRx may cover a significant portion of one patient’s medication protocol while offering fewer relevant options for another.

Because the medications and prices available through TrumpRx can change, patients should search the platform for their specific prescriptions and compare available cash prices with their insurance coverage and other fertility medication savings programs.

What Is TrumpRx Exactly?

TrumpRx is a pricing and access platform that helps patients find lower-cost medications through negotiated discounts on certain brand-name drugs and cash-price comparisons for generic medications.

Importantly, TrumpRx does not sell or dispense medications. It is not a pharmacy, mail-order service, or insurance plan. Instead, the platform displays available pricing offers and provides information on how patients can access those discounted prices. For certain brand-name medications, TrumpRx offers discounts based on manufacturer agreements established through the administration’s Most Favored Nation initiative. The platform has since expanded to include cash-price comparisons for hundreds of generic medications, including prices available through participating pharmacies and discount programs.

Patients still work with their healthcare providers, receive prescriptions as usual, and obtain medications through participating pharmacies or manufacturer programs.

How Does TrumpRx Work?

TrumpRx includes both manufacturer-negotiated discounts on certain brand-name drugs and cash-price comparisons for generic medications. The administration’s Most Favored Nation pricing model is the basis for its negotiated brand-name discounts. 

In simple terms, this approach aims to reduce prescription drug costs by aligning U.S. prices more closely with the lower prices paid in other developed countries. Under the program, the federal government negotiates directly with pharmaceutical manufacturers to offer reduced pricing on certain medications. Those pricing agreements are then made available to patients through the TrumpRx platform. For generic medications, TrumpRx also allows patients to compare cash prices available through local pharmacies, delivery services, and private pharmacy discount programs.

Pricing and fulfillment depend on the specific medication and type of offer involved. TrumpRx itself does not process prescriptions or dispense medications.

Instead, patients may access discounted prices in several ways, including:

• Coupon-based pricing that can be used at participating pharmacies
• Direct access through manufacturer websites or partner pharmacy networks

The exact process varies depending on the medication and offer listed on TrumpRx.

How Do I Use TrumpRx for Fertility Medications?

If you find one of your prescribed fertility medications on TrumpRx, the next step depends on the type of pricing offer available. Key factors to keep in mind include:

• Patients do not need to create an account or register to access pricing information. The platform is free to use.
• Patients still need a valid prescription from their healthcare provider. TrumpRx does not generate prescriptions, transfer prescriptions, or function as a pharmacy.
• Depending on the medication, patients may obtain discounted pricing through participating pharmacies or through manufacturer-directed purchasing channels.
• TrumpRx displays out-of-pocket cash prices rather than processing purchases through insurance. If you have prescription drug coverage, compare the TrumpRx price with your insurance copay to determine which may cost less.

Because the program continues to evolve, patients should review the specific requirements associated with each medication listed on the platform.

What Are the Limitations of TrumpRx for IVF Patients?

TrumpRx is still a developing platform, and additional medications, pricing options, and pharmacy partners may be added over time.

While fertility medications are available through TrumpRx, the platform does not include every medication that may be prescribed during IVF. Because treatment protocols vary, the potential savings will depend on the specific medications and dosages your fertility specialist recommends.

TrumpRx also displays out-of-pocket prices rather than functioning as an insurance benefit. If you have prescription drug coverage, the TrumpRx price may or may not be lower than your insurance copay. Prices and pharmacy availability can also vary by medication and location.

For these reasons, TrumpRx may reduce fertility medication costs for some patients without necessarily providing the lowest price or covering every medication needed during an IVF cycle.

TrumpRx IVF and Fertility Medication FAQs

What This Means for Fertility Patients Right Now

TrumpRx gives fertility patients another way to potentially reduce the out-of-pocket cost of medications used during IVF. However, how much you can save depends on your individual treatment protocol, insurance coverage, and the prices available for your prescribed medications.

If you’re considering TrumpRx, talk with your fertility clinic before filling your prescriptions. Your care team can help you understand which medications are part of your treatment plan and compare the available options for accessing them affordably.

TrumpRx also isn’t the only resource available for reducing fertility medication costs. Patients within The Prelude Network® have access to InspireRx, a pharmacy benefits platform designed to simplify prescription fulfillment and help patients access fertility medications at more affordable prices through a network of trusted pharmacies.

Rather than delaying fertility care while waiting for additional medications or programs to become available, you can work with your care team to explore the cost-saving options available to you now.